開催日時	2024/07/14(日曜日) - 2024/07/19(金曜日)
開催場所	Stonehill College, United States
申請代表者	飛松 裕基（生存圏研究所）
所内担当者	飛松 裕基（生存圏研究所）
関連ミッション	ミッション1 環境診断・循環機能制御 ミッション2 太陽エネルギー変換・高度利用 ミッション5 高品位生存圏
関連分野	木質科学、植物科学、農芸化学、高分子科学、材料科学

詳細は、こちらのページをご参照ください。
https://www.grc.org/lignin-conference/2024/

概要

Lignin Gordon Research Conferenceでは、植物バイオマスの主要成分であるリグニンの基礎と応用をテーマに、植物学、微生物学、化学、工学に渡る広範な専門領域で活躍するリグニン研究者を世界各国から招集し、最新の研究成果を共有し、植物バイオマス利用のブレークスルーに繋げるための分野横断的討論を行った。さらに、若手人材育成を主目的とするサテライト会議Lignin Gordon Research Seminarも開催した。

目的と具体的な内容

ゴードン研究会議（Gordon Research Conference；GRC）は、歴史と権威のある国際研究集会であり、ゴードン財団より厳選された特に重要度の高いscienceの専門分野について、世界各国から当該分野を代表する研究者を招集し、密な討論を行うものである。Lignin GRCは、植物バイオマスの主要成分であるリグニンの基礎と応用を主題とするGRCであり、植物学、微生物学、化学、工学に渡る広範な専門領域で活躍するリグニン研究者を世界各国から集め、最新の研究成果を共有し、植物バイオマス利用のブレークスルーに繋げるための分野横断的討論を行うことを趣旨としている。3度目の開催となる2024 Lignin GRCでは、申請者（Yuki Tobimatsu, 京都大学生存圏研究所）は、共同議長のLaura Bartley博士（米国ワシントン州立大学）と Jeremy Luterbacher博士（スイス連邦工科大学ローザンヌ校）、共同副議長のMojgan Nejad（米国ミシガン州立大学）とともに、共同副議長を務めた。世界23カ国から約150名のリグニン研究者が参加し、リグニンの生合成、代謝工学、分析手法、微生物分解、化学分解、マテリアル利用といった基礎研究から、企業研究者を中心とした産業利用といった、応用展開まで幅広い分野を網羅する8つのセッションにおいて、5日間に渡って、合計35件の招待講演と85件のポスター発表が行われた。また、若手人材育成を主目的とするサテライト会議Lignin Gordon Research Seminar（2024 Lignin GRS）を初めて開催した。2024 Lignin GRSには、主に大学院生とポスドク研究員ら約50名が参加し、2日間に渡って、14件の招待講演と約30件のポスター発表が行われた。

生存圏科学の発展や関連コミュニティの形成への貢献

本研究集会は、多岐に渡るリグニンの基礎・応用研究に関わるものであり、特にミッション1「環境診断・循環機能制御」、ミッション2「太陽エネルギー変換・高度利用」、ミッション5-2　「脱化石資源社会の構築（植物、バイオマス、エネルギー、材料）」をはじめとする生存圏ミッション活動と深く関係する。とりわけ、本研究集会の重要トピックの一つであるリグニンの利用法開発は、ミッション2やミッション5-2が掲げる「植物バイオマスの高度利用」の最重要課題の一つであり、その推進に直接的に関係するものである。約１週間に渡る、植物バイオマス（特にリグニン）研究を先導するトップ研究者らの密な研究討論と交流が行われ、ミッション活動やフラッグシップ共同研究の発展を含む生存圏科学の深化は勿論のこと、生存圏科学コミュニティーの発展、特に国際ネットワークの拡大と強化やコミュニティーにおける生存圏研究所のプレゼンス強化に寄与したと考えている。また、若手人材育成を主眼とするサテライト会議（Lignin GRS）やダイバーシティ関係のミニシンポジウム（GRC Power Hour）も企画され、生存圏科学に関わる人材育成やダイバーシティ推進にも寄与するものであった。

写真

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July 14, Sunday

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2:00 pm - 9:00 pm Arrival and Check-in 6:00 pm - 7:00 pm Dinner 7:30 pm - 7:40 pm Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs 7:40 pm - 9:30 pm Keynote Session: The Science and Engineering of Lignin Discussion Leaders: Mojgan Nejad (Michigan State University, United States) and Yuki Tobimatsu (Kyoto University, Japan) 7:40 pm - 7:50 pm Introduction by Discussion Leader 7:50 pm - 8:25 pm Lacey Samuels (University of British Columbia Vancouver, Canada) "The Dangerous Game of Lignification in Plants" 8:25 pm - 8:35 pm Discussion 8:35 pm - 9:10 pm Claudia Crestini (Università Ca' Foscari, Italy) "Deciphering the Lignin Enigma: Unraveling and Tailoring Supramolecular Aggregation for Advanced Materials Development" 9:10 pm - 9:20 pm Discussion 9:20 pm - 9:30 pm General Discussion

July 15, Monday

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7:30 am - 8:30 am Breakfast 8:30 am - 9:00 am Group Photo 9:00 am - 12:30 pm Lignin Biosynthesis and Biotechnology Discussion Leader: Claire Halpin (University of Dundee, United Kingdom) 9:00 am - 9:10 am Introduction by Discussion Leader 9:10 am - 9:30 am Jack Wang (North Carolina State University, United States) "Multiplex CRISPR-Editing of Wood for Sustainable Production of Bioenergy and Biomaterials" 9:30 am - 9:40 am Discussion 9:40 am - 10:00 am Laigeng Li (Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, China) "The Biosynthesis and Regulation of Lignin in a Cell Type-Specific Manner" 10:00 am - 10:10 am Discussion 10:10 am - 10:20 am Pingping Ji (Kyoto university, Japan) "Short talk: Manipulation of Lignin Aromatic Composition in Grasses: Elimination of Syringyl Lignin Units in Rice Mutants Deficient in Grass-Specific Lignin Decoration" 10:20 am - 10:25 am Discussion 10:25 am - 10:55 am Coffee Break 10:55 am - 11:15 am Chang-Jun Liu (Brookhaven National Laboratory, United States) "Redox Partners and Electron Transfer Chains for Phenylpropanoid-Lignin Biosynthesis" 11:15 am - 11:25 am Discussion 11:25 am - 11:45 am Jaime Barros-Rios (University of Missouri, United States) "Clinal Variation in Lignin Composition Among Natural Poplar Variants" 11:45 am - 11:55 am Discussion 11:55 am - 12:15 pm Clint Chapple (Purdue University, United States) "Lignin-Modified Plants Reveal That Phenylpropanoids May Be Regulators of Plant Growth" 12:15 pm - 12:25 pm Discussion 12:25 pm - 12:30 pm General Discussion 12:30 pm - 1:30 pm Lunch 1:30 pm - 4:00 pm Free Time 3:00 pm - 4:00 pm The GRC Power Hour™ Organizers: Stefania Bertella (VTT Technical Research Center of Finland, Finland) and Davinia Salvachua (National Renewable Energy Laboratory, United States) 4:00 pm - 6:00 pm Poster Session 6:00 pm - 7:00 pm Dinner 7:30 pm - 9:30 pm Lignin Plant Biology Discussion Leader: Xu Li (North Carolina State University, United States) 7:30 pm - 7:40 pm Introduction by Discussion Leader 7:40 pm - 7:50 pm Sungjun Choung (Korea Advanced Institute of Sciecne and Technology, South Korea) "The Molecular Mechanism of Defensive Lignification against the Stem-Boring Herbivore in Wild Tobacco Stem" 7:50 pm - 7:55 pm Discussion 7:55 pm - 8:15 pm Hiroshi Maeda (University of Wisconsin - Madison, United States) "Evolution of the Aromatic Amino Acid and Lignin Metabolic Network across Poaceae and Poales" 8:15 pm - 8:25 pm Discussion 8:25 pm - 8:45 pm Misato Ohtani (The University of Tokyo, Japan) "Plastic Regulation of Transcriptional Networks for Lignin is the Key for Plant Environmental Adaptation" 8:45 pm - 8:55 pm Discussion 8:55 pm - 9:15 pm Deanna Funnell-Harris (United States Department of Agriculture , United States) "Does Altering Sorghum Phenylpropanoid Metabolism Affect Pathogen Resistance?" 9:15 pm - 9:25 pm Discussion 9:25 pm - 9:30 pm General Discussion

July 16, Tuesday

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7:30 am - 8:30 am Breakfast 9:00 am - 12:30 pm Tools for Analysis of Lignin Discussion Leader: Tuo Wang (Michigan State University, United States) 9:00 am - 9:10 am Introduction by Discussion Leader 9:10 am - 9:30 am Gabriel Paës (INRAE, France) "Fluorescence Tools to Shed Light on Lignin" 9:30 am - 9:40 am Discussion 9:40 am - 10:00 am Dan Aoki (Nagoya University, Japan) "Chemical Mapping of Mobile Components" 10:00 am - 10:10 am Discussion 10:10 am - 10:20 am Oliver Musl (BOKU University, Vienna, Austria) "In Another Dimension: Functionality Profiling and Mapping of Lignin Structure via Multidimensional Liquid Chromatography" 10:20 am - 10:25 am Discussion 10:25 am - 10:55 am Coffee Break 10:55 am - 11:15 am Josh Vermaas (Michigan State University, United States) "Lignin Modeling and Modification In Silico for Enhanced Biomaterials" 11:15 am - 11:25 am Discussion 11:25 am - 11:45 am Antje Potthast (University of Natural Resources and Life Sciences, Austria) "Perspectives on Lignin Dispersities" 11:45 am - 11:55 am Discussion 11:55 am - 12:15 pm Monika Österberg (Aalto University, Finland) "Analysing and Controlling Lignin’s and Lignin Nanoparticle's Interfacial Interactions for Optimized Performance in Applications" 12:15 pm - 12:25 pm Discussion 12:25 pm - 12:30 pm General Discussion 12:30 pm - 1:30 pm Lunch 1:30 pm - 4:00 pm Free Time 4:00 pm - 6:00 pm Poster Session 6:00 pm - 7:00 pm Dinner 7:30 pm - 9:30 pm Lignin from an Industrial Perspective Discussion Leader: Chip Frazier (Virginia Tech, United States) 7:30 pm - 7:40 pm Introduction by Discussion Leader 7:40 pm - 7:50 pm Sandip Singh (University of Kansas, United States) "Formulation of High-Performance Renewable Adhesives from Lignin and Amino Acids" 7:50 pm - 7:55 pm Discussion 7:55 pm - 8:05 pm Sami Kazaz (Lawrence Berkeley National Laboratory, United States) "Beta-Ketoadipate (ßKA) Synthesis in Lignin Bioengineered Plants for Sustainable Nylon Production" 8:05 pm - 8:10 pm Discussion 8:10 pm - 8:25 pm Kait Kaarel Puss (Fibenol OÜ, Estonia) "Deploying Lignin Analytics in Fibenol's Industrial Biorefinery" 8:25 pm - 8:30 pm Discussion 8:30 pm - 8:45 pm Jean-Pierre Lindner (Baden Aniline, Germany) "Lignin Valorisation in the Chemical Industry: Concepts and Use Cases" 8:45 pm - 8:50 pm Discussion 8:50 pm - 9:05 pm Edward Lewis (Canon Virginia, Inc., United States) "Valorizing Macromolecular Lignin: A Manufacturers Perspective" 9:05 pm - 9:10 pm Discussion 9:10 pm - 9:25 pm Joann Sutyak (Hexion, United States) "The Current Outlook of Lignin in Industrial Adhesives" 9:25 pm - 9:30 pm Discussion

July 17, Wednesday

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7:30 am - 8:30 am Breakfast 9:00 am - 12:30 pm Chemical Lignin Depolymerization Discussion Leader: Sari Rautiainen (VTT Technical Research Centre of Finland Ltd, Finland) 9:00 am - 9:10 am Introduction by Discussion Leader 9:10 am - 9:30 am Peter Deuss (Rijksuniversiteit Groningen, The Netherlands) "Mild Lignin Fractionation, Modification and Depolymerization" 9:30 am - 9:40 am Discussion 9:40 am - 10:00 am Xiao Zhang (Washington State University, United States) "Can We Overcome Lignin Heterogeneity? A Perspective from Deep Eutectic Solvent Depolymerization" 10:00 am - 10:10 am Discussion 10:10 am - 10:20 am Claire Laura Bourmaud (EPFL , Switzerland) "Exploring Structure-Reactivity Relationships in Lignin Depolymerization through Integrated Coupled Graph Modeling and Kinetic Monte Carlo Simulation" 10:20 am - 10:25 am Discussion 10:25 am - 10:55 am Coffee Break 10:55 am - 11:15 am Michael Stone (National Renewable Energy Laboratory, United States) "Analysis-Guided Developments in Lignin-First Biorefining" 11:15 am - 11:25 am Discussion 11:25 am - 11:45 am Katalin Barta (Karl-Franzens University of Graz, Austria) "Creating New Chemical Space through Lignin Valorization" 11:45 am - 11:55 am Discussion 11:55 am - 12:15 pm Joseph Samec (Stockholm University, Sweden) "Lignin-First: Beyond Monophenols and Towards Sustainability" 12:15 pm - 12:25 pm Discussion 12:25 pm - 12:30 pm General Discussion 12:30 pm - 1:30 pm Lunch 1:30 pm - 4:00 pm Free Time 4:00 pm - 6:00 pm Poster Session 6:00 pm - 7:00 pm Dinner 7:30 pm - 9:30 pm Lignin-Based Product and Material Design Discussion Leader: Agnieszka Brandt-Talbot (Imperial College London, United Kingdom) 7:30 pm - 7:40 pm Introduction by Discussion Leader 7:40 pm - 7:50 pm Yukiko Enomoto (The University of Tokyo, Japan) "Super-High-Performance Bio-Based Plastics Derived from Lignin" 7:50 pm - 7:55 pm Discussion 7:55 pm - 8:15 pm Wilfred Vermerris (University of Florida, United States) "The Use of Lignin in Biomedical Applications" 8:15 pm - 8:25 pm Discussion 8:25 pm - 8:45 pm Florent Allais (AgroParisTech, France) "Combining Green Chemistry and Biotechnology to Turn Lignins and Naturally Occurring Phenolics into Value-Added Chemicals and Materials" 8:45 pm - 8:55 pm Discussion 8:55 pm - 9:15 pm Mika Sipponen (Stockholm University, Sweden) "Colloidal Lignin Particles at Bio-Interfaces" 9:15 pm - 9:25 pm Discussion 9:25 pm - 9:30 pm General Discussion

July 18, Thursday

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7:30 am - 8:30 am Breakfast 8:30 am - 9:00 am Business Meeting Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s) 9:00 am - 12:30 pm Enzymatic and Microbial Lignin Transformation Discussion Leader: Eric Hegg (Michigan State University, United States) 9:00 am - 9:10 am Introduction by Discussion Leader 9:10 am - 9:30 am Timothy Donohue (University of Wisconsin - Madison, United States) "Mining Bacterial Genomes to Generate Valuable Products from Lignin" 9:30 am - 9:40 am Discussion 9:40 am - 10:00 am Mirjam Kabel (Wageningen University and Research, The Netherlands) "Insights into Fungal Oxidation-Driven Delignification, and Subsequent Use of (Degraded) Lignin as a Carbon Source" 10:00 am - 10:10 am Discussion 10:10 am - 10:20 am Megan Wolf (The University of British Columbia, Canada) "Characterization of a Cytochrome P450 That Catalyzes the O-Demethylation of Lignin-Derived Benzoates" 10:20 am - 10:25 am Discussion 10:25 am - 10:55 am Coffee Break 10:55 am - 11:15 am Alissa Bleem (National Renewable Energy Laboratory, United States) "Combining Chemo- and Bio-Catalytic Approaches for Conversion of Lignin to Value-Added Products" 11:15 am - 11:25 am Discussion 11:25 am - 11:45 am Takehito Nakazawa (Kyoto University, Japan) "Insights form Molecular Genetics Studies in White-Rot Fungi" 11:45 am - 11:55 am Discussion 11:55 am - 12:15 pm Ligia Martins (ITQB NOVA, Portugal, Portugal) "New Engineered Microbial Enzymes for Lignin Valorization" 12:15 pm - 12:25 pm Discussion 12:25 pm - 12:30 pm General Discussion 12:30 pm - 1:30 pm Lunch 1:30 pm - 4:00 pm Free Time 4:00 pm - 6:00 pm Poster Session 6:00 pm - 7:00 pm Dinner 7:30 pm - 9:30 pm Process Engineering and Systems Analysis Discussion Leader: Hemant Choudhary (Joint BioEnergy Institute / Sandia National Laboratories, United States) 7:30 pm - 7:40 pm Introduction by Discussion Leader 7:40 pm - 7:50 pm Wouter Arts (KU Leuven, Belgium) "Feasibility of Wood as a Renewable Carbon Feedstock for the Production of Chemicals in Europe" 7:50 pm - 7:55 pm Discussion 7:55 pm - 8:15 pm David Hodge (Montana State University, United States) "Impact of Processing History and Recovery Conditions on Lignin Coagulation, Filterability, Color, and Chemical Properties" 8:15 pm - 8:25 pm Discussion 8:25 pm - 8:45 pm Sander Van den Bosch (KU Leuven / Biocon, Belgium) "Beyond the Bench: Integrating Process Modelling and Experimental Scale-Up to Advance RCF Biorefining" 8:45 pm - 8:55 pm Discussion 8:55 pm - 9:15 pm Pahola Thathiana Benavides (Argonne National Laboratory, United States) "Life-Cycle Analysis of Lignin Conversion to Sustainable Aviation Fuel Blendstocks" 9:15 pm - 9:25 pm Discussion 9:25 pm - 9:30 pm General Discussion

July 19, Friday

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7:30 am - 8:30 am Breakfast 9:00 am Departure

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